# -*- mode: org -*- * Version 2.2 ** User visible changes - NEW FEATURE: getPseudovalue can be used to extract pseudo-observations corresponding to the net Benefit. - NEW FEATURE: model.tte can now accept survreg objects. ** Internal change - fix operator option moving it to the C++ code. - c++ for the competing risk has been updated to compute the influence function - calculation of the survival/cumulative incidence function/influence function of the survival model for the Peron's scoring rule has been re-written. * Version 2.1 ** User visible changes - NEW FEATURE (version 2.1.3): simBuyseTest now can simulate time to event endpoints and categorical endpoints that are correlated (argument argsTTE, element rho.T). The user interface of argument argsTTE has also been modified. - NEW FEATURE (version 2.1.5): simBuyseTest simulates time to event endpoints using a Weibull distribution. The argument rates are now called scales (i.e. correspond to the inverse of the previous arguments). ** Internal change - add options precompute in BuyseTest.options (version 2.1.4): when set to TRUE, the integrals over the survival and their derivatives are pre-computed instead of being computed on the fly when scoring the pairs. - fix c++ memory issue (version 2.1.1-2.1.3) - fix calculation of probability of being uninformative (version 2.1.0) * Version 2.0 ** User visible changes - NEW FEATURE: powerBuyseTest now support multiple sample size when using the Peron's scoring rule. - Fix issue related to powerBuyseTest (issue #6 on Github) ** Internal change - powerBuyseTest has been partially re-written. Should be easier to read/debug now. - add argument engine to BuyseTest.options to switch between the new C++ implementation (looping first over pairs and then over endpoints) and the old C++ implementation (looping first over endpoints and then over pairs). The new is more memory efficient but is not available when correction.uninf>0. - old implementation is more memory efficient when using method.inference="u-statistic" and scoring.rule="Peron" with several endpoints thanks to the use of sparse matrices to store partial derivative regarding nuisance parameter. * Version 1.9 ** User visible changes - NEW FEATURE (1.9.1): summary and confint can now display the results for proportion in favor of treatment (also called Mann-Whitney statistic) or control - NEW FEATURE (1.9.0): studentized permutation tests are now available (method.inference = "studentized permutation"). - method.inference="u-statistic" is now the default options ** Internal change - reorganize R function files. * Version 1.8 ** User visble changes - NEW FEATURE (1.9.0): function simCompetingRisks to simulate data with competing risks under proportional sub-hazard - NEW FEATURE (1.9.0): add argument cluster in confint and iid - NEW FEATURE (1.8.3): function auc - NEW FEATURE: method.inference="u-statistic" gives valid results when using scoring.rule="Peron". - NEW FEATURE (1.8.1): scoring.rule="Peron" also works in presence of competing risk (method.inference="u-statistic" does not work in this case though). - CHANGE: The group variable in simBuyseTest is treatment instead of Treatment. - CHANGE: The stratification of the resampling procedure is now defined via the argument strata.resampling. In particular this enables to performed a bootstrap stratified on the treatment variable. - CHANGE (1.8.2): argument censoring has been renames status in the formula interface. Now the user can specify censoring = "left" or "right" to deal with right or left censoring (left censoring is only implemented for the Gehan's scoring rule) - Fix issue related to rates in simBuyseTest (issue #4 on Github) - fix bug in BuyseTest (argument strata.resampling) - Add reference in the description as suggested by CRAN. - Update vignette. ** Internal change - Fix clang-UBSAN issue in the C++ code. - Second order H-projection for scoring.rule="Peron" has been fixed. - To a large extend, the C++ code performing the GPC has been re-written to be able to compute the iid decomposition for the scores when using the Peron's scoring rule. * Version 1.7 ** User visble changes - method.inference="asymptotic" becomes method.inference="u-statistic" - argument method.tte becomes scoring.rule. - NEW FEATURE: coef function - NEW FEATURE: iid function - NEW FEATURE: option hierarchical in BuyseTest - NEW FEATURE: studentized bootstrap - NEW FEATURE: gaussian permutation ** Internal change - fix bug in the computation of the asymptotic variance + add tests - faster computation of the iid (done in the C++ code) * Version 1.6 ** Internal change - simplify C++ code. * Version 1.5 ** User visble changes - Argument statistic now takes values netBenefit or winRatio (instead of netChance or winRatio). - NEW FEATURE: standard errors/p.values/confidence intervals can now be computed without resampling setting the option method.tte to asymptotic - NEW FEATURE: a function powerBuyseTest has been added to perform simulation studies with BuyseTest (e.g. compute power, coverage or bias). ** Internal change - improve the management of the weights of the pairs from one endpoint to another. * Version 1.4 ** User visble changes - BuyseTest function - NEW FEATURE: Instead of estimating the survival curves on the data used for the GPC, BuyseTest can use pre-defined survival models for method "Peron" (argument model.tte). - NEW FEATURE: methods getSurvival to access the survival probability used by BuyseTest. - NEW FEATURE: getPairScore to access the score of each pair. - NEW FEATURE: argument method.uninf in BuyseTest enables to re-attribute the uninformative scores to favorable/unfavorable/neutral. ** Internal change - improve initSurvival and the computation of the Peron (C++ code) - change the handling of NA in the survival when using method.tte="Peron" (C++ code) - change the way neutralAsUninf is implemented (C++ code) * Version 1.3 ** User visble changes - BuyseTest function - NEW FEATURE: boostrap resampling (method.inference = "boostrap") - NEW FEATURE: confint method to extract confidence intervals - NEW FEATURE: BuyseTest can handle competing risks (experimental) - argument n.permutation becomes n.resampling - argument method becomes method.tte - add argument method.inference to choose how to compute pvalues and CI. - option method.tte="Peto" and method.tte="Efron" have been removed. ** Internal change - reorganize BuyseTest into BuyseTest and .BuyseTest. Make initalization and testing of the arguments independent - remove dependency on tcltk. - confidence intervals and p.values are computed outside BuyseTest, when calling summary. * Version 1.2 ** User visble changes - BuyseTest function - add argument keepComparison, operator. - argument n.bootstrap becomes n.permuation - argument neutralAsUninf becomes neutral.as.uninf - nicer display with summary - lighter display when printing the object ** Internal change - reorganize the tests * Version 1.1 - add a formula argument to the BuyseTest function. This can be used instead of the treatment, endpoint, threshold, type, censoring, and strata argument to specify the prioritized endpoints. - unify the C++ code, add a threshold for considering a pair non-informative (w>1e-12). May induce differences with previous versions in the index of uniformative pairs. - uses prodlim instead of survival to compute the KM estimates. - Add a neutralAsUnif argument to the BuyseTest function to decide whether the analysis should continue on lower priority when a pair is classified as neutral