DoseFinding: Planning and Analyzing Dose Finding Experiments

The DoseFinding package provides functions for the design and analysis of dose-finding experiments (with focus on pharmaceutical Phase II clinical trials). It provides functions for: multiple contrast tests, fitting non-linear dose-response models (using Bayesian and non-Bayesian estimation), calculating optimal designs and an implementation of the MCPMod methodology (Pinheiro et al. (2014) <doi:10.1002/sim.6052>).

Version: 0.9-17
Depends: lattice, mvtnorm, R (≥ 2.15.0)
Suggests: numDeriv, Rsolnp, quadprog, parallel, multcomp
Published: 2019-11-16
Author: Bjoern Bornkamp ORCID iD [aut, cre], Jose Pinheiro [ctb], Frank Bretz [ctb]
Maintainer: Bjoern Bornkamp <bbnkmp at gmail.com>
License: GPL-3
NeedsCompilation: yes
Materials: ChangeLog
In views: ClinicalTrials, ExperimentalDesign
CRAN checks: DoseFinding results

Downloads:

Reference manual: DoseFinding.pdf
Package source: DoseFinding_0.9-17.tar.gz
Windows binaries: r-devel: DoseFinding_0.9-17.zip, r-devel-gcc8: DoseFinding_0.9-16.zip, r-release: DoseFinding_0.9-17.zip, r-oldrel: DoseFinding_0.9-17.zip
OS X binaries: r-release: DoseFinding_0.9-17.tgz, r-oldrel: DoseFinding_0.9-17.tgz
Old sources: DoseFinding archive

Reverse dependencies:

Reverse depends: MCPModGeneral, TestingSimilarity
Reverse imports: clinDR, clustDRM, LRcontrast, uniReg

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