colocPropTest: Proportional Testing for Colocalisation Analysis

Colocalisation analysis tests whether two traits share a causal genetic variant in a specified genomic region. Proportional testing for colocalisation has been previously proposed [Wallace (2013) <doi:10.1002/gepi.21765>], but is reimplemented here to overcome barriers to its adoption. Its use is complementary to the fine- mapping based colocalisation method in the 'coloc' package, and may be used in particular to identify false "H3" conclusions in 'coloc'.

Version: 0.9.1
Depends: magrittr, data.table
Imports: car, coloc, graphics, stats, utils
Suggests: knitr, plotrix, testthat (≥ 3.0.0)
Published: 2024-06-11
DOI: 10.32614/CRAN.package.colocPropTest
Author: Chris Wallace ORCID iD [aut, cre]
Maintainer: Chris Wallace <chris.x.wallace at>
License: GPL (≥ 3)
NeedsCompilation: no
Materials: README
CRAN checks: colocPropTest results


Reference manual: colocPropTest.pdf
Vignettes: Proportional colocalisation


Package source: colocPropTest_0.9.1.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): colocPropTest_0.9.1.tgz, r-oldrel (arm64): colocPropTest_0.9.1.tgz, r-release (x86_64): colocPropTest_0.9.1.tgz, r-oldrel (x86_64): colocPropTest_0.9.1.tgz


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